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KMID : 0356919920250040648
Korean Journal of Anesthesiology
1992 Volume.25 No. 4 p.648 ~ p.655
Evaluation of Anesthetic Effects of Enflurane by Spictrum Analysis of Rat EEG




Abstract
To evaluate the depth of enflurane anesthesia, spectrum analysis of rat EEG was used.
Bipolar EEG was recorded through one lead form rat scalp during inhalation with 1, 2, 3 and 4% of enflurane, and analysed to prduce the spectrum from which the density of each band (delta 1-3.25 Hz, theta 3.5-7.75 Hz, alpha 8-12.75 Hz, beta 1
13-17.75
Hz, beta 2 18-20.75 Hz, and beta 3 21-31.75Hz) and total density, and median power frequency were calculated.
Differences among the EEG patterns, which were represented by F values through discriminant analysis of those 8 variables, in each level of anesthesia were significant among all concentrations except between 1% and 2% enflurane administration.
The results suggest that the discriminant analysis for the Eeg parameters derived from power spectrum analysis can apply to determine the level of enflurane anesthesia.
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